Yes. Both extremes--too much or too little body fat--put an individual at risk for serious medical and/or psychological conditions. Having a very low body fat percentage, particularly for women, can result in musculoskeletal problems and osteoporosis. And it can upset the hormonal balance causing loss of menstruation. Striving for extremely low body fat can also result in severe eating disorders, such as anorexia nervosa, bulimia, and binge-eating which have significant health implications.